Two Cases of Near-Tetraploidy in Acute Leukemias of Ambiguous Lineage

Two Cases of Near-Tetraploidy in Acute Leukemias of Ambiguous Lineage

Acute leukemia of ambiguous lineage (ALAL) is a rare subtype of acute leukemias that does not show any clear evidence of differentiation along a single lineage [1]. Although both numerical and structural chromosomal abnormalities are commonly associated with acute and chronic hematologic malignancies, near-tetraploidy has been reported rarely (1.2% of AML cases) [2, 3]. Adult AML patients with ...

Acute leukemias of ambiguous origin.

OBJECTIVES This session of the Society for Hematopathology/European Association for Haematopathology Workshop focused on acute leukemias of ambiguous origin. METHODS We provide an overview of mixed-phenotype acute leukemia (MPAL) as recognized in the current World Health Organization classification and summarize diagnostic criteria for major categories of MPAL: B/myeloid, T/myeloid, B/T, and ...

Biphenotypic, bilineal, ambiguous or mixed lineage: strange leukemias!

synthesis of platinum nanostructures in two phase system

چکیده پلاتین، فلزی نجیب، پایدار و گران قیمت با خاصیت کاتالیزوری زیاد است که کاربرد های صنعتی فراوانی دارد. کمپلکس های پلاتین(ii) به عنوان دارو های ضد سرطان شناخته شدند و در شیمی درمانی بیماران سرطانی کاربرد دارند. خاصیت کاتالیزوری و عملکرد گزینشی پلاتین مستقیماً به اندازه و- شکل ماده ی پلاتینی بستگی دارد. بعضی از نانو ذرات فلزی در سطح مشترک مایع- مایع سنتز شده اند، اما نانو ساختار های پلاتین ب...

MicroRNA profiling can classify acute leukemias of ambiguous 1 lineage as either acute myeloid leukemia or acute lymphoid 2 leukemia

MicroRNA profiling can classify acute leukemias of ambiguous 1 lineage as either acute myeloid leukemia or acute lymphoid 2 leukemia. 3 4 David C. de Leeuw, Willemijn van den Ancker, Fedor Denkers, Renée X. de Menezes, 5 Theresia M. Westers , Gert J. Ossenkoppele , Arjan A. van de Loosdrecht 1 and Linda 6 Smit . 7 8 Authors’ Affiliation: 9 1 Department of Hematology, VU University Medical Cente...